For masochistic people that like to complete every single quest possible, as efficiently as possible.
Side quests are listed in alphabetical order.
Tutorial & Main Storyline
Tutorial Quests
Name/Quest Giver/Reward:
- Ain’t That a Kick in the Head – Doc Mitchell – Vault 21 Jumpsuit, Pip-Boy, 18 caps, 6 bobby pins, various possible items depending on character build
- Back in the Saddle – Sunny Smiles – 50 caps, Varmint Rifle, 30 5.56mm Rounds. Possible extra 60 5.56mm rounds. Possible 50 XP + Goodsprings fame from saving settler from geckos.
- By a Campfire on the Trail – Sunny Smiles – Healing Powder
Main Storyline Quests
Name/Quest Giver/Reward:
- They Went That-a-Way – Doc Mitchell – 1,000 XP
- Ring-a-Ding-Ding! – Jessup – 1,000 or 1,200 XP
Mr. House
Name/Quest Giver/Reward:
- The House Always Wins I – Mr. House – 600 XP, 1000 caps, Lucky 38 Presidential Suite
- The House Always Wins II – Mr. House – 500 XP
- The House Always Wins III – Mr. House – 250 XP, NCR/Legion infamy
- The House Always Wins IV – Mr. House – Nothing. Completing this quest makes NCR or Legion endings unachievable.
- The House Always Wins V – Mr. House – Brotherhood of Steel infamy
- The House Always Wins VI – Mr. House – Nothing
- The House Always Wins VII – Mr. House – Nothing
- All Or Nothing – Mr. House – Ending
Yes Man / Independent
Name/Quest Giver/Reward:
- Wild Card: Ace in the Hole – Yes Man – Nothing
- Wild Card: Change in Management – Yes Man – 300 XP, some NCR/Legion infamy, one dead Mr. House.
- Wild Card: You and What Army? – Yes Man – 750 XP or 500 XP
- Wild Card: Side Bets – Yes Man – Legion infamy. Completing this quest makes NCR or Legion endings unachievable.
- Wild Card: Finishing Touches – Yes Man – 500 XP, NCR infamy
- You’ll Know It When It Happens – Yes Man – 1000 XP, NCR fame. (This quest is an optional objective in Wild Card: Finishing Touches.)
- No Gods, No Masters – Yes Man – Ending
NCR
Name/Quest Giver/Reward:
- Things That Go Boom – Ambassador Crocker – 200 XP, between 300 and 500 caps, NCR fame
- Kings’ Gambit – Ambassador Crocker – 1300 XP, 600 caps, either NCR fame or NCR infamy depending on how you complete the quest.
- For the Republic – Colonel Moore – 475 XP, NCR fame. Completing this quest makes Legion and Mr. House endings unachievable.
- You’ll Know It When It Happens – Ranger Grant – 1000 XP, NCR fame (This quest is part of For the Republic.)
- Eureka! – General Oliver – Ending
Caesar’s Legion
Name/Quest Giver/Reward:
- Render Unto Caesar – Caesar – 500 XP, Legion fame, NCR infamy. Completing this quest makes NCR and Mr. House endings unachievable.
- Et Tumor, Brute? – Caesar – 1000 XP, 10 Legion Aureus
- Arizona Killer – Caesar/Lucius – Legion fame
- Veni, Vidi, Vici – Legate Lanius – Ending
Side Quests
Name/Quest Giver/Reward:
- A Valuable Lesson – Festus – 1600 XP, 1500 caps, Pew Pew
- Aba Daba Honeymoon – Diane – Great Khans fame, Turbo recipe/250 caps, 750 caps, Khan Trick
- Ant Misbehavin’ – Raquel – 300 XP, Boomers fame
- Anywhere I Wander – Renolds – 100 XP, NCR fame
- Back in Your Own Backyard – Ranger Milo – 150 XP, 50 caps, NCR fame, Legion infamy
- Beyond the Beef – Mortimer/Heck Gunderson – White Glove Society fame. 100 XP/250 caps OR 500 XP/500 caps + The Strip fame.
- Birds of a Feather – Gloria Van Graff – 600 XP, Van Graff combat armor, 1000 caps, Cass will die if you complete this quest and will no longer be available as a companion.
- Bitter Springs Infirmary Blues – Markland – 2 Stimpaks, 4 Rad-X, 4 RadAway, NCR fame
- Bleed Me Dry – Red Lucy – 1650 XP, 5200 caps, Dinner Bell, hunting revolver, hunting rifle, possible sex with Red Lucy
- Booted – Boxcars – 100 XP, Powder Gangers fame
- Boulder City Showdown – Lieutenant Monroe – 300 XP, NCR fame and/or Great Khans fame
- Bye Bye Love – Joana – 200 XP, 600 to 1000 caps
- Can You Find it in Your Heart? – Ranger Jackson – 200 XP, 100 caps, NCR fame, service rifle, 72 5.56mm AP rounds, 2 weapon repair kits, 2 caravan lunches
- Classic Inspiration – Michael Angelo – 950 XP, 1250 caps, The Strip fame
- Climb Ev’ry Mountain – Captain Gilles – 100 XP, NCR fame
- Cold, Cold Heart – Vulpes Inculta – 150 XP, possible Legion fame
- Come Fly With Me – Manny Vargas/No-Bark Noonan – 1000 XP, Novac fame
- Crazy, Crazy, Crazy – Neil – 1000 XP
- Cry Me a River – Jerry the Punk – 350 XP
- Debt Collector – Francine Garrett – 600 XP, 300 caps, Freeside fame, player housing in Atomic Wrangler
- Don’t Make a Beggar of Me – Melissa – 100 XP/150 caps, Great Khans fame, various chems OR 100 XP, NCR fame, positive karma
- Eye for an Eye – First Sergeant Astor – 500 XP/200 caps, NCR fame OR 500XP/150 caps, Legion fame
- Eyesight to the Blind – Elder McNamara – Brotherhood of Steel membership, T-45d power armor, Power Armor Training
- Flags of Our Foul-Ups – Sergeant McCredie – Various XP, NCR fame
- G.I. Blues – The King – 500 to 1500 XP, Freeside fame, one favor from The King
- Ghost Town Gunfight – Trudy – Goodsprings fame, Powder Gangers infamy
- Guess Who I Saw Today – Doctor Henry – 500 XP, Oh Baby!
- Hard Luck Blues – Morgan Blake – 200 or 250 XP, NCR fame
- High Times – Julie Farkas – 500 XP, Followers of the Apocalypse fame
- How Little We Know – Cachino/Joana – 400 caps or 50 Gomorrah chips, Pimp-Boy 3 Billion, The Strip fame
- I Don’t Hurt Anymore – Lieutenant Gorobets – 250 XP, NCR fame
- I Fought the Law – Eddie – 300 or 200 XP, 100 caps, 1 Mentats, 1 Psycho, and 1 Buffout.
- I Hear You Knocking – Lucius – 100 XP, Legion fame
- I Put a Spell on You – Colonel Hsu/Vulpes Inculta – 600 XP, 250 caps, and NCR fame OR 550 XP, 150 caps, and Legion fame
- Keep Your Eyes on the Prize – Ranger Ghost – 100 XP, NCR fame
- Left My Heart – Frank Weathers/Mrs. Weathers – 1000 XP, 50 caps OR 300 XP, 50 caps
- Medical Mystery – Dr. Richards – 300 XP, NCR fame
- My Kind of Town – Deputy Beagle/Johnson Nash – 300 XP
- No, Not Much – Captain Gilles – 300 XP, NCR fame, positive karma
- Oh My Papa – Regis – 700 XP, 200 caps
- One for my Baby – Boone – 150 XP, 100 caps, 1st Recon Beret, Boone as a companion
- Pheeble Will – Walter Phebus – 375 XP, possible 400 caps
- Pressing Matters – Alice McLafferty – 100 XP, 500 caps, NCR fame
- Restoring Hope – Major Polatli/Quartermaster Mayes – 300 XP, NCR fame, Liberator
- Return to Sender – Tech Sergeant Reyes – 500 or 600 XP, NCR fame
- Run Goodsprings Run – Joe Cobb – Powder Ganger fame, Goodsprings infamy
- Someone to Watch Over Me – Crandon – 1000 caps, 150 XP
- Still in the Dark – Elder McNamara – 1000 XP, 1400 caps, Brotherhood of Steel fame, Brotherhood of Steel safehouse key
- Sunshine Boogie – Loyal – 300 XP, Boomers fame
- Talent Pool – Tommy Torini – 550 XP, 150 caps, The Strip fame
- Tend to Your Business – Head Paladin Hardin – Brotherhood of Steel membership, T-45d power armor, Power Armor Training
- That Lucky Old Sun – Fantastic/Lieutenant Haggerty – 350 XP, NCR fame or Followers of the Apocalypse fame, possible Big Book of Science, stimpaks, doctor’s bags
- The Coyotes – Captain Parker – 250 XP, 150 caps
- The Finger of Suspicion – Vulpes Inculta – 100 XP, Legion fame
- The Legend of the Star – Festus – Starts A Valuable Lesson
- The Moon Comes Over the Tower – Emily Ortal – 500 XP, Followers of the Apocalypse fame
- The White Wash – Carrie Boyd – Key to MP confiscated goods trunk
- There Stands the Grass – Thomas Hildern – 1200 or 1500 XP, 1200 or 2000 caps
- Three-Card Bounty – Major Dhatri – 750 caps, 300 XP, NCR fame
- Unfriendly Persuasion – Marcus – 350 XP, possible 2500 or 3000 caps
- Volare! – Pearl – 500 XP, Boomer flightsuit, Boomers helmet, Boomers fame
- Wang Dang Atomic Tango – James Garrett – 450 XP, 150 or 400 caps, Freeside fame
- We Are Legion – Dead Sea – 300 XP, Legion fame, Liberator
- We Will All Go Together – First Sergeant Astor – 250 XP, 250 caps, service rifle
- Wheel of Fortune – Logan – 100 XP, various random weapons
- Why Can’t We Be Friends? – Philip Lem/Samuel Cooke – 300 XP, Powder Gangers fame
- You Can Depend on Me – Alice McLafferty – 550 XP, 500 caps
- Young Hearts – Jack – 300 XP, 470 caps, Boomers fame
Companion Quests
Name/Quest Giver/Reward:
- ED-E My Love – Johnson Nash/ED-E – ED-E upgrades
- Heartache By the Number – Cass – 500 XP, Calm Heart perk for Cass or Hand of Vengeance perk for Cass and NCR infamy
- I Forgot to Remember to Forget – Boone – 500 XP, 1st Recon survival armor for Boone or 1st Recon assault armor for Boone
- I Could Make You Care – Veronica – 1000 XP, Bonds of Steel perk for Veronica or Causeless Rebel perk for Veronica
- For Auld Lang Syne – Arcade Gannon – 500 XP, Remnants power armor, Power Armor Training, possible Gannon family tesla armor
- Nothin’ But a Hound Dog – The King – Rex as a companion, and one of three different perks for Rex
Dead Money
Name/Quest Giver/Reward:
- Sierra Madre Grand Opening! – Sierra Madre Broadcast – Holorifle, Dead Money Jumpsuit
- Find Collar 8: “Dog” – Father Elijah – Dog/God as a companion
- Find Collar 12: Christine – Father Elijah – 200 XP, Christine as a companion
- Find Collar 14: Dean Domino – Father Elijah – Dean Domino as a companion
- Fires in the Sky – Father Elijah – 800 XP
- Mixed Signals – Father Elijah – 800 XP
- Strike Up the Band – Father Elijah – 800 XP
- Trigger the Gala Event – Father Elijah – 1600 XP
- Put the Beast Down – Father Elijah – Various XP/Karma
- Last Luxuries – Father Elijah – Nothing
- Curtain Call at the Tampico – Father Elijah – Nothing
- Heist of the Centuries – Father Elijah – 37 gold bars, DLC completion
Honest Hearts
Name/Quest Giver/Reward:
- Happy Trails Expedition – Happy Trails Expedition Broadcast – 225 caps
- Arrival at Zion – Jed Masterson – Variable XP
- Bighorners of the Eastern Virgin – Follows-Chalk – Variable XP, .45 Auto Pistol, War Club
- Gone Fishin’ – Joshua Graham – Variable XP
- Roadside Attraction – Joshua Graham – Variable XP
- Tourist Trap – Joshua Graham – Variable XP
- Deliverer of Sorrows – Joshua Graham – Variable XP
- River Monsters – Daniel – Variable XP
- The Advance Scouts – Daniel – Variable XP
- The Grand Staircase – Daniel – Variable XP
- The Treacherous Road – Daniel – Variable XP
- Civilized Man’s Burden – Follows-Chalk – Variable XP
- A Family Affair – Waking Cloud – Variable XP
- Rite of Passage – White Bird/Waking Cloud – Variable XP, She’s Embrace
- Gathering Storms – Daniel – Variable XP
- Flight from Zion – Daniel – Variable XP, Honest Hearts footlocker, DLC completion
- Crush the White Legs – Joshua Graham – Variable XP, Honest Hearts footlocker, DLC completion
Old World Blues
Name/Quest Giver/Reward:
- Midnight Science Fiction Feature! – Mysterious Broadcast – Variable XP
- Welcome to the Big Empty – Self – Variable XP, possible Sonic Emitter, K9000 cyberdog gun, various caps and ammo
- X-2: Strange Transmissions! – Doctor Klein – X-2 Antenna
- X-8: High School Horror! – Doctor Klein – Gabriel’s Bark frequency for Sonic Emitter
- X-13: Attack of the Infiltrator! – Doctor Klein – Stealth Suit Mk. II
- X-8 Data Retrieval Test – X-8 Research Center terminal – Variable XP, DNAgent perk
- Sonic Emitter Upgrade – Doctor Klein – Nothing
- Project X-13 – Doctor Klein – Upgraded Stealth Suit Mk. II
- All My Friends Have Off Switches – Sink Central Intelligence Unit – Various Sink services
- Influencing People – The Sink – Upgrades to Sink services
- Field Research – Sink Central Intelligence Unit – Variable XP, Sonic Emitter frequencies, Sink farming capabilities
- Picking Your Brains – Doctor Klein – Variable XP, several new quests
- When Visitors Attack! – Doctor Klein – Variable XP
- A Brain’s Best Friend – Doctor Borous – Variable XP
- What’s In a Name? – Doctor 0 – Variable XP, 1 scrap metal, 1 scrap electronics
- On the Same Wavelength – Doctor 8 – Variable XP
- He Came… And Went – Doctor Dala – 450 XP
- Coming Out of Her Shell – Doctor Dala – Various energy weapons ammo
- Old World Blues – Doctor Klein – Big Mountain Transportalponder, DLC completion
Lonesome Road
Name/Quest Giver/Reward:
- The Reunion – Radio Signal – 10 XP
- The Silo – Pip-Boy – 2,200 XP
- The Job – Ulysses – 2,310 XP
- The Launch – Ulysses – 4,400 XP
- The Divide – Pip-Boy – 4,400 XP
- The Tunnelers – ED-E – 2,200 XP
- The Courier – Pip-Boy – 2,200 XP
- The End – Pip-Boy – 5,000 XP, Lonesome Road footlocker, 1 SPECIAL point, Brotherhood of Steel fame, Followers of the Apocalypse fame, DLC completion.
- The Apocalypse – Pip-Boy – 5,000 XP, Lonesome Road footlocker, 1 SPECIAL point, access to Long 15 and/or Dry Wells, NCR fame/Legion infamy or vice versa, possible Boomers/Powder Gangers fame, DLC completion.
Original Link – Continuation of discussion